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. Author manuscript; available in PMC: 2019 Jun 13.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2017 May 24;44(10):1682–1691. doi: 10.1007/s00259-017-3720-6

Table 2.

Summary of investigated metrics for the baseline and early response FMISO dynamic PET scans in tumors (n=135).

Tumor-to-blood Ratio k3 (min−1) Distribution volume K1 (min−1) vB
Baseline (mean intratumor) 1.35±0.31 0.0029± 0.0022 0.97± 0.14 0.38± 0.17 0.20± 0.10
Early response (mean intratumor) 1.12±0.15 0.0020± 0.0016 0.91± 0.14 0.41± 0.21 0.21± 0.11
p-value* <0.01 <0.01 <0.01 0.20 0.28
Mean difference −0.22±0.26 −0.0009± 0.0021 −0.06± 0.14 0.03± 0.21 0.01± 0.12
Baseline (voxelwise) 1.48±0.49 0.0039± 0.0037 0.97± 0.18 0.35± 0.21 0.19± 0.12
Early response (voxelwise) 1.18±0.21 0.0021± 0.0022 0.92± 0.18 0.38± 0.25 0.22± 0.14
*

Unpaired 2-tailed Student t test.