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. Author manuscript; available in PMC: 2019 Jun 13.
Published in final edited form as: Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;86:203–210. doi: 10.1016/j.pnpbp.2018.06.004

Table 3.

Striatal and ACC GABA levels.

MDD (n = 20)
 HC (n = 16)
 p
Mean SD Mean SD
Striatal GABA/W 4.61 × 10−3*** 0.66 × 10−3 3.88 × 10−3*** 0.45 × 10−3 0.001*
ACC GABA/W 2.78 × 10−3 0.33 × 10−3 3.02 × 10−3 0.50 × 10−3 0.07**

Abbreviations: ACC = anterior cingulate cortex; GABA = γ-aminobutyric acid; HC = healthy controls; MDD = major depressive disorder; SD = standard deviation; W = unsuppressed voxel tissue water signal.

*

Significant difference between MDD and HC groups (p < .05).

**

Approaches significant difference between MDD and HC groups (p < .10).

***

Significant difference between striatal and ACC GABA levels (p < .0005).