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. Author manuscript; available in PMC: 2019 Jun 13.
Published in final edited form as: Science. 2018 Oct 26;362(6413):464–467. doi: 10.1126/science.aau6324

Fig. 3. Increased BP variability in conscious nodose/petrosal ganglia-specific dKO mice.

Fig. 3.

A, Continuous measurements of mean arterial pressure (MAP) and HR over 72 h, binned by hour. The differences between groups were significant during night (gray shading, two-way ANOVA, means ± s.e.m). B, Average MAP and HR during day (6am-6pm) and night (6pm-6am). C, sBRS, expressed as change in PI (ms) per change in systolic BP (mmHg), was significantly reduced in dKO mice (n = 17) compared to WT (n = 15). D, Frequency distribution histogram of the systolic blood pressure from 72 h. Red arrows indicate wider distribution of BP in dKO mice. E, BP variability reported as standard deviation from 72-h period. F, Maximum and minimum BP values. P values are indicated in the bars. *p < 0.05, **p < 0.01 and ***p < 0.001, n.s. is not significant. Unpaired Student’s t-test unless indicated otherwise, means ± s.e.m. n = 7–17.