Plasma levels of cholesterol (a), NEFA (b), triacylglycerol (c) and LDL-cholesterol (d) in rats at the end of the 8 week (56 day) experimental protocol. Data are expressed as mean ± SEM, n = 6/group. *p < 0.05 vs vehicle-treated WKY rats;†p < 0.05 vs vehicle-treated SHROB rats. White squares, vehicle-treated WKY rats; black squares, vehicle-treated SHROB rats; grey squares, RB394-treated SHROB rats