Table 1. Single-nucleotide polymorphisms suggestively associated with spontaneous preterm birth.

Chr	Locusa	SNPb	Reference allele	Allele frequency	Odds ratio (95% confidence interval)	p
4	SLIT2	rs116461311	C	0.05	3.43 (2.01–5.86)	1.58E-6
7	SUGCT	rs57670997	Del	0.68	0.56 (0.44–0.71)	1.79E-6
9	Intergenic (LOC105376188, LOC105376190)	rs35464758	Del	0.05	2.82 (1.67–4.80)	1.82E-6
5	Intergenic (LOC100128898, LOC100130177)	rs4704916	A	0.19	1.91 (1.45–2.52)	2.22E-6
10	EXOSC1-ZDHHC16-MMS19-UBTD1c	rs10678727	Ins	0.58	1.77 (1.40–2.23)	2.39E-6
2	Intergenic (THUMPD2, SLC8A1)	rs17480505	C	0.35	1.72 (1.36–2.17)	3.88E-6
21	DSCAM	rs9974083	A	0.24	1.73 (1.34–2.24)	4.32E-6
2	PPP1CB-SPDYA-TRMT61B-WDR43c	rs200334508	G	0.87	0.51 (0.37–0.71)	4.44E-6
11	DLG2	rs202170665	Ins	0.08	0.40 (0.25–0.65)	4.59E-6
10	Intergenic (RBM17, LOC1019280803)	rs10905856	T	0.08	2.28 (1.53–3.41)	4.87E-6
10	ABI1	rs72385215	Del	0.33	0.56 (0.44–0.72)	4.89E-6
10	ADAMTS14	rs12765664	A	0.93	0.40 (0.26–0.61)	5.95E-6
8	DLC1	rs7006225	A	0.77	0.56 (0.43–0.72)	6.99E-6
6	Intergenic (LOC105377949, LOC107986634)	rs1418269	C	0.69	1.73 (1.34–2.22)	7.51E-6
18	DLGAP1	rs610269	G	0.54	0.61 (0.49–0.76)	7.97E-6
2	NCKAP5	rs1966628	T	0.45	1.64 (1.31–2.05)	8.29E-6
20	HSPA12B	rs58505239	T	0.20	1.75 (1.34–2.29)	8.66E-6
3	Intergenic (LOC105377173, ROBO1)	rs115723230	T	0.03	3.33 (1.70–6.54)	8.70E-6
1	EIF1P3	rs539974331	Del	0.04	3.57 (1.95–6.55)	8.92E-6
9	SVEP1	rs199638820	Del	0.56	1.61 (1.29–2.02)	9.56E-6
2	ALK	rs7608573	T	0.20	0.52 (0.38–0.70)	9.99E-6

^aRespective gene shown for SNPs within genes; two nearest genes shown in parentheses for intergenic SNPs.

^bSNP with the most significant signal shown for each locus.

^cAssociation signal spans the indicated genes.