Table 3. Suggestively associated SNPs that overlap with cis eQTLs.
| SNP information | cis-eQTL information | ||||
|---|---|---|---|---|---|
| GWAS region | SNPa | p in GWAS | eGene | eQTL pb | Tissue |
| EXOSC1-ZDHHC16-MMS19-UBTD1 | rs7897727c | 2.03E-06 |
ZDHHC16 MMS19 FRAT1 |
2.0E-18 1.7E-07 2.0E-05 2.6E-06 5.0E-06 |
Testis Adipose–Subcutaneous Breast–Mammary tissue Lung Cells–Transformed fibroblasts |
| DSCAM | rs9974083 | 4.32E-06 | PCP4 | 2.3E-07 | Artery—Tibial |
| Intergenic, chr6 | rs1418269 | 7.51E-06 | RP1-142L7.5 | 3.4E-05 | Esophagus—Muscularis |
| NCKAP5 | rs1966628d | 8.29E-06 | NCKAP5 | 1.3E-05 | Testis |
| HSPA12B | rs58505239 | 8.66E-06 |
CDC25B ADAM33 |
1.8E-07 1.3E-06 2.9E-06 |
Adipose–Subcutaneous Artery—Tibial Esophagus—Muscularis |
aTop eQTL SNP shown for each region.
beQTL data from GTEx Portal V7.
c Altogether, 15 suggestively associated SNPs within EXOSC1-ZDHHC16-MMS19-UBTD1 region colocalized with eQTLs; these SNPs are eQTLs for ZDHHC16, MMS19, FRAT1, ANKRD2, UBTD1, and RRP12
dAltogether, eight suggestively associated SNPs within NCKAP5 region are eQTLs for NCKAP5.