Table 1. Patient characteristics at baseline.

	AMIS		ARIP		CLOZ		OLAN		QUET		RISP		RLAI		ZIPR		OLAI		PALI		PP1M
total population (N)	N = 736		N = 921		N = 713		N = 2650		N = 2229		N = 2096		N = 869		N = 164		N = 393		N = 599		N = 844
1. Gender	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%
male	281	38%	348	38%	314	44%	1160	44%	767	34%	835	40%	414	48%	61	37%	187	48%	230	38%	357	42%
2. Age at baseline	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD
age at baseline (years), mean (SD)	49,3	15,0	43,7	13,7	49,2	15,5	47,9	14,7	53,6	17,4	52,1	17,0	46,7	14,6	46,8	14,2	43,7	13,6	46,5	13,4	47,2	13,0
	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.	median	perc.
age at baseline (years), median (25–75 percentile)	50	38–60	42	33–54	50	37–60	49	37–58	54	40–66	53	39–64	46	35–58	46,5	36–56	43	32–54	46	36–56	47	38–57
	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%
Age = 0–19			20	2%			30	1%	16	1%	29	1%
Age = 20–29	68	9%	127	14%	67	9%	287	11%	185	8%	191	9%	115	13%	16	10%	67	17%	63	11%	82	10%
Age = 30–39	141	19%	252	27%	145	20%	514	19%	334	15%	333	16%	196	23%	34	21%	99	25%	137	23%	173	20%
Age = 40–49	151	21%	194	21%	126	18%	551	21%	386	17%	344	16%	181	21%	38	23%	90	23%	136	23%	216	26%
Age = 50–59	184	25%	216	23%	179	25%	701	26%	522	23%	511	24%	190	22%	48	29%	74	19%	161	27%	212	25%
Age = 60–69	120	16%	82	9%	122	17%	365	14%	346	16%	354	17%	132	15%	15	9%	52	13%	71	12%	129	15%
Age = 70–79	49	7%	23	2%	44	6%	152	6%	235	11%	196	9%	46	5%					24	4%	25	3%
Age = 80–89	13	2%			19	3%	46	2%	186	8%	123	6%
3. Time since diagnosis a	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD	mean	SD
no. of months since 1st recorded F20 diagnosis—Mean(SD)	64,13	31,98	59,31	32,89	70,28	28,23	58,70	34,20	51,88	35,66	54,71	35,56	58,83	34,84	66,88	28,99	61,92	35,08	63,09	32,15	76,67	30,33
	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%	n	%
n (%) patients with < 6 months	58	7,88%	87	9,45%	38	5,33%	337	12,72%	393	17,63%	337	16,08%	129	14,84%			52	13,23%	54	9,02%	42	4,98%
n (%) patients with 6-<12 months	23	3,13%	36	3,91%	13	1,82%	98	3,70%	78	3,50%	90	4,29%	32	3,68%			10	2,54%	19	3,17%
n (%) patients with 12-<24 months	52	7,07%	80	8,69%	29	4,07%	201	7,58%	207	9,29%	175	8,35%	52	5,98%	10	6,10%	30	7,63%	39	6,51%	32	3,79%
n (%) patients with 24-<36 months	37	5,03%	68	7,38%	27	3,79%	160	6,04%	190	8,52%	130	6,20%	45	5,18%	13	7,93%	16	4,07%	30	5,01%	38	4,50%
n (%) patients with 36-<48 months	48	6,52%	52	5,65%	36	5,05%	141	5,32%	141	6,33%	114	5,44%	47	5,41%			21	5,34%	31	5,18%	34	4,03%
n (%) patients with >48 months	518	70,38%	598	64,93%	570	79,94%	1713	64,64%	1220	54,73%	1250	59,64%	564	64,90%	124	75,61%	264	67,18%	426	71,12%	689	81,64%

^a time since first diagnosis appearance in the database—does not necessarily indicate the first diagnosis ever, as date of first diagnosis is not recorded; data before 2002 were not available