TABLE 4.
Laboratory Parameter Changes (mITT Population)
| Subgroup | Hemoglobin, g/dL | CRP, mg/dL | ||
|---|---|---|---|---|
| Etanercept | Placebo | Etanercept | Placebo | |
| Baseline value | ||||
| Median | 10.80 | 10.70 | 7.90 | 8.80 |
| Percentile, 25th, 75th | 9.60, 11.4 | 9.90, 11.2 | 5.02, 15.40 | 6.12, 17.70 |
| Change from baseline to wk 1 | ||||
| Median | 0.00 | −0.20 | −7.15 | −8.00 |
| Percentile, 25th, 75th | −1.10, 0.80 | −1.3, 0.70 | −13.69, −4.46 | −16.00, −4.50 |
| Within normal range at wk 1, n (%) | 25 (27) | 24 (26) | 63 (69) | 55 (60) |
| Change from baseline to wk 2 | ||||
| Median | 0.30 | 0.35 | −7.20 | −8.00 |
| Percentile, 25th, 75th | −0.50, 1.10 | −0.45, 0.90 | −14.75, −4.58 | −17.00, −4.80 |
| Within normal range at wk 2, n (%) | 36 (36) | 41 (42) | 80 (85) | 77 (82) |
| Change from baseline to wk 6 | ||||
| Median | 1.60 | 1.35 | −7.20 | −7.80 |
| Percentile, 25th, 75th | 0.60, 2.20 | 0.60, 1.90 | −14.60, −4.00 | −14.80, −5.60 |
| Within normal range at wk 6, n (%) | 79 (82) | 76 (82) | 90 (95) | 87 (95) |
No significant differences were found across treatment groups at any visit.