Gonzalez Garcia 1994

Methods	Randomised, double blind, active (ketorolac) control, single oral dose. Study duration 6 h. Baseline PI = moderate or severe Self assessment at t = 0, 0.5, 1.0, then hourly up to 6 h.
Participants	Orthopaedic surgery N = 60 M 27, F 33 Mean age = 41 years
Interventions	Dipyrone, 500 mg, n = 30 Ketorolac 10 mg, n = 30
Outcomes	PI: non standard 5 point scale (none‐very severe) PR: standard 5 point scale (0‐4) Use of rescue medication Adverse events Withdrawals
Notes	Oxford Quality Score: R1, DB1, W1. Total = 3
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not reported
Allocation concealment (selection bias)	Unclear risk	Not reported
Blinding (performance bias and detection bias) All outcomes	Unclear risk	Not reported