Time course of DMI (Panel A), milk yield (Panel B), milk fat yield (Panel C), and milk fat concentration (Panel D) of cows fed sodium bicarbonate at 3.2% of diet DM (control; NaHCO), sodium acetate at 2.9% of diet DM (NaAc), and calcium butyrate at 2.5% of diet DM (CaBu; equal carbon mass of NaAc; n = 12 per treatment). Least-square means and standard errors are shown and means that do not share a superscript differ within timepoint (P < 0.05).