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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Mol Cancer Ther. 2019 Apr 8;18(6):1045–1056. doi: 10.1158/1535-7163.MCT-18-0146

Figure 2: The effect of UCHL5 and PSMD14 knockdown on NB cell proliferation and USP14 knockdown inhibits anchorage-independent growth.

Figure 2:

A, B. Immunoblotting assay showing UCHL5 and PSM14 knockdown in NGP and SH-SY5Y cells by lentivirus sh-UCHL5 and sh-PSMD14. Cell growth curve assay shows a proliferation defect in two UCHL5 knockdown NB cells. The cell counting kit-8 (CCK-8) was used to determine cell viability. Error bars represent SDs of six samples. **P<0.01 and ***P<0.001. C-H. Soft agar assay showing reduced colony formation in USP14-knockdown cells. Colony numbers were quantified. These experiments were performed in triplicate and reported as mean with SDs. ***P<0.001.