Table 2:
Presence of Seizure | Time to First Seizure | ||||||
---|---|---|---|---|---|---|---|
Proportions (N = 210) |
OR | 95% (LCL, UCL) |
p-value | HR | 95% (LCL, UCL) |
p-value | |
Clinical Features | |||||||
Male vs. Female | 0.42/0.26 | 2.01 | (1.12, 3.64) | 0.021 | 1.78 | (1.10, 2.90) | 0.018 |
Preterm vs. Term | 0.23/0.39 | 0.48 | (0.22, 0.96) | 0.044 | 0.58 | (0.31, 1.07) | 0.082 |
EEG Indication | |||||||
Suspected seizure or both indications vs. Encephalopathy | 0.39/0.19 | 2.73 | (1.28, 6.36) | 0.012 | 2.46 | (1.22, 4.95) | 0.011 |
Encephalopathy or both indications vs. Suspected seizure alone | 0.30/0.37 | 0.73 | (0.38, 1.33) | 0.301 | 0.72 | (0.43, 1.19) | 0.197 |
High Risk Characteristics | |||||||
Hypoxic ischemic encephalopathy (HIE) vs. No HIE | 0.35/0.34 | 1.04 | (0.52, 2.02) | 0.913 | 0.97 | (0.57, 1.68) | 0.934 |
Therapeutic Hypothermia (TH) vs. No TH | 0.33/0.35 | 0.93 | (0.41, 2.01) | 0.851 | 0.86 | (0.45, 1.64) | 0.650 |
ECMO vs. Patients not on ECMO | 0.37/0.34 | 1.14 | (0.46, 2.72) | 0.765 | 1.03 | (0.51, 2.07) | 0.926 |
Cardiac Arrest (CA) vs. No CA | 0.39/0.35 | 1.10 | (0.39, 2.88) | 0.842 | 0.97 | (0.44, 2.12) | 0.940 |
CHD vs. No CHD | 0.29/0.36 | 0.74 | (0.31, 1.65) | 0.470 | 0.74 | (0.37, 1.48) | 0.389 |
EEG Background Features | |||||||
Excessive discontinuity vs. Normal | 0.46/0.11 | 7.10 | (3.34, 16.62) | <0.001 | 5.17 | (2.53, 10.57) | <0.001 |
Depressed and undifferentiated vs. Normal | 0.77/0.11 | 27.78 | (7.09, 142.84) | <0.001 | 11.42 | (4.63, 28.14) | <0.001 |
Burst suppression vs. Normal | 0.70/0.11 | 19.45 | (4.58, 103.85) | <0.001 | 10.26 | (3.81, 27.68) | <0.001 |
Extremely low voltage/isoelectric vs. Normal | 0.33/0.11 | 4.17 | (0.18, 47.98) | 0.263 | 4.99 | (0.63, 39.55) | 0.127 |
MFS vs. Absence of MFS | 0.40/0.27 | 1.78 | (0.99, 3.25) | 0.054 | 1.58 | (0.98, 2.57) | 0.062 |
Focal vs. Absence of focal findings | 0.39/0.34 | 1.24 | (0.49, 2.97) | 0.642 | 1.19 | (0.59, 2.38) | 0.632 |
Sleep wake cycling | 0.25/0.54 | 0.29 | (0.16, 0.53) | <0.001 | 0.39 | (0.25, 0.63) | <0.001 |