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. Author manuscript; available in PMC: 2019 Aug 11.
Published in final edited form as: Oncogene. 2019 Feb 11;38(24):4700–4714. doi: 10.1038/s41388-019-0745-2

Figure 6. KPNB1 knockdown attenuates PCa tumor growth in vivo.

Figure 6.

A) Crystal violet staining showing the growth of C42B-scramble or C42B-shKPNB1 cell line. B) Immunoblotting results showing protein level of KPNB1, Cyclin B1, CDK1, pRCC1 of C42B-scramble and C42B-shKPNB1 cell lines. α-Tubulin was used as internal control. C). Immunoblotting results showing NF-κB p50 within nuclear of C42B-scramble and C42B-shKPNB1. Lamin A/C was used as internal control. D) IHC staining of KPNB1, Cyclin D1, Cyclin B1, CDK1, pRCC1 of tumor sections. E) Statistical results of positive stained cells of tumor sections. F and G) Tumor burdens of C42B-scramble and C42B-shKPNB1 through subcutaneous injection were dissected and weighted. *p <0.05, **p<0.01, *** p<0.001.