Table 4.
Viral load characteristics within established DBS TFV-DP thresholds among 137 women. Odds ratios (OR) predicting viral load <50, <400 and <1000 copies/mL are presented.
| TFV-DP threshold (approximate doses per week1) | <350 (<2) | 350–699 (2–3) | 700–1249 (4–6) | ≥1250 (7) |
|---|---|---|---|---|
| Total number of women | 47 | 19 | 41 | 30 |
| Median viral load log10 copies/mL (IQR) | 3.7 (2.8–4.6) | 1.3 (1.3–1.3) | 1.3 (1.3–1.3) | 1.3 (1.3–1.3) |
| Median viral load copies/mL (IQR) | 12200 (618–40027) | 20 (20–20) | 20 (20–20) | 20 (20–20) |
| Viral load <50 copies/mL | ||||
| Viral load <50 copies/mL, n (%) | 7 (15) | 16 (84) | 36 (88) | 29 (97) |
| OR (95% CI) | Ref | 30 (7–133) | 41 (12–141) | 166 (19–1421) |
| aOR2 (95% CI) | Ref | 37 (8–178) | 47 (13–175) | 175 (20–1539) |
| Viral load <400 copies/mL | ||||
| Viral load <400 copies/mL, n (%) | 12 (26) | 17 (89) | 39 (95) | 30 (100) |
| OR (95% CI) | Ref | 31 (6–159) | 72 (15–352) | Omitted |
| aOR2 (95% CI) | Ref | 47 (8–287) | 100 (17–579) | Omitted |
| Viral load <1000 copies/mL | ||||
| Viral load <1000 copies/mL, n (%) | 10 (21) | 17 (89) | 39 (95) | 30 (100) |
| OR (95% CI) | Ref | 25 (5–123) | 57 (12–272) | Omitted |
| aOR2 (95% CI) | Ref | 31 (6–167) | 64 (12–330) | Omitted |
1
As previously described by Castillo-Mancilla et al (CID, 2018)
2
Adjusted for age and duration on ART