Table 2.

Results of mixed effects models, testing for correlation of age at onset within families after adjusting for epilepsy type, sex, ascertainment site, history of febrile seizure, and age at last observation.

Abbreviations: ICC, intraclass correlation coefficient.

Model	N of individuals (families)	ICC	p-valuea
All families	1,008 (300)	0.17	< 0.001
Generalized families	373 (115)	0.29	<0.001
- Additional adjustment for subtype/syndromeb		0.11	0.02
Focal families	206 (62)	0.19	0.002
- Additional adjustment for subtype/syndromeb		0.15	0.01

^aLikelihood ratio test

^bFor list of the epilepsy syndromes/subtypes within generalized and focal epilepsies, see Table 1 and Methods.