Table 1.
Baseline intracerebral hemorrhage characteristics by blood type
| All ICH N = 272 | Type-O N =146 | Type-A N =82 | Type-B N =34 | Type-AB N =10 | p value | |
|---|---|---|---|---|---|---|
| Age: mean (SD) | 66 (16) | 65 (16) | 67 (14) | 66 (15) | 59 (18) | 0.42 |
| Female: N (%) | 125 (46) | 66 (45) | 32 (39) | 21 (62) | 6 (60) | 0.12 |
| Race: N (%) | ||||||
| White | 66 (24) | 37 (25) | 22 (27) | 6 (18) | 1 (10) | 0.05 |
| Black | 79 (29) | 42 (29) | 22 (27) | 10 (29) | 5 (50) | |
| Hispanic | 111 (41) | 60 (41) | 35 (43) | 14 (41) | 2 (20) | |
| Other/unknown | 16 (6) | 7 (5) | 3 (4) | 4 (12) | 2 (20) | |
| Medical history: N (%) | ||||||
| Dyslipidemia | 69 (25) | 34 (23) | 22 (27) | 11 (32) | 2 (20) | 0.69 |
| Coronary artery disease | 39 (14) | 19 (13) | 12 (15) | 7 (21) | 1 (10) | 0.71 |
| Atrial fibrillation | 31 (11) | 17 (12) | 9 (11) | 4 (12) | 1 (10) | 0.99 |
| Hypertension | 217 (80) | 117 (80) | 62 (76) | 29 (85) | 9 (90) | 0.54 |
| Diabetes | 82 (30) | 50 (34) | 23 (28) | 8 (24) | 1 (10) | 0.27 |
| Prior ischemic stroke | 30 (11) | 17 (12) | 8 (10) | 3 (9) | 2 (20) | 0.79 |
| Prior ICH | 15 (6) | 10 (7) | 2 (2) | 3 (9) | 0 (0) | 0.25 |
| Medication history: N (%) | ||||||
| Antiplatelet | 104 (38) | 56 (38) | 33 (40) | 12 (35) | 3 (30) | 0.91 |
| Anticoagulation | 38 (14) | 19 (13) | 13 (16) | 5 (15) | 1 (10) | 0.92 |
| Statin | 55 (20) | 30 (21) | 15 (18) | 7 (21) | 3 (30) | 0.85 |
| Clinical/radiographic | ||||||
| GCS: median (IQR) | 11 (7–15) | 10 (7–14) | 11 (7.5–15) | 10 (6–14) | 14 (4–15) | 0.67 |
| ICH Score: median (IQR) | 2 (1–3) | 2 (1–3) | 2 (1–3) | 2 (1–3) | 2 (1–3) | 0.53 |
| ICH volume (mL): median (IQR) | 13 (4.2–33.8) | 12.3 (4–33) | 14 (4.9–35) | 13.8 (5.2–29) | 16.7 (7.8–69.8) | 0.87 |
| DNR: N (%) | 71 (26) | 43 (29) | 18 (22) | 7 (21) | 3 (30) | 0.55 |
| Deep location: N (%) | 168 (62) | 89 (61) | 49 (60) | 24 (71) | 6 (60) | 0.73 |
| Lobar location: N (%) | 75 (28) | 39 (27) | 26 (32) | 7 (21) | 3 (30) | 0.66 |
| Brainstem location: N (%) | 15 (6) | 9 (6) | 3 (4) | 2 (6) | 1 (10) | 0.79 |
| Infratentorial location: N (%) | 14 (5) | 9 (6) | 4 (5) | 1 (3) | 0 (0) | 0.62 |
| IVH: N (%) | 134 (51) | 70 (50) | 41 (52) | 17 (50) | 6 (60) | 0.94 |
| EVD placement: N (%) | 81 (30) | 48 (33) | 20 (25) | 10 (29) | 3 (30) | 0.65 |
| Time to baseline CT (hours): median (IQR) | 4.9 (1.6–10.7) | 5.5 (1.8–11) | 5.9 (1.4–11.7) | 4.5 (1.5–7.3) | 3.8 (1.8–8.6) | 0.62 |
| Admission SBP: mean (SD) | 187 (40) | 185 (40) | 184 (38) | 193 (40) | 212 (38) | 0.14 |
| Admission DBP: mean (SD) | 101 (25) | 100 (27) | 99 (23) | 103 (23) | 111 (27) | 0.57 |
| Laboratory testing: mean (SD) | ||||||
| Hemoglobin (g/dL) | 13.4 (1.9) | 13.3 (2.0) | 13.4 (1.8) | 13.6 (1.9) | 13.5 (2.1) | 0.89 |
| PT (sec) | 15.3 (5.9) | 15.2 (5.3) | 15.4 (6.6) | 15.6 (7.3) | 15.9 (6.3) | 0.97 |
| PTT (sec) | 30.5 (6.9) | 30.5 (6.6) | 30.6 (7.3) | 30.8 (8.2) | 28.4 (4.9) | 0.88 |
| INR | 1.3 (0.7) | 1.2 (0.6) | 1.3 (0.7) | 1.3 (0.8) | 1.3 (0.7) | 0.96 |
| Platelet count (103/uL) | 218 (71) | 215 (68) | 218 (71) | 229 (88) | 215 (72) | 0.79 |
| Rhesus positive: N (%) | 244 (90) | 128 (88) | 75 (92) | 31 (91) | 10 (100) | 0.37 |
CI confidence interval, DBP diastolic blood pressure, DNR do-not-resuscitate, EVD extraventricular drain, GCS Glasgow coma scale, HE hematoma expansion, ICH intracerebral hemorrhage, INR international normalized ratio, IQR interquartile range, IVH intraventricular hemorrhage, mRS modified Rankin Score, OR odds ratio, PT prothrombin time, PTT partial thromboplastin time, SD standard deviation, SBP systolic blood pressure