Table 2.
Description of time dependent variables of engraftment and acute GVHD among the four groups.
| Variable | VEP-BSI | LEP-BSI | Both-BSI | No BSI |
|---|---|---|---|---|
| Number of patients | 1,492 | 824 | 340 | 4,472 |
| Days to first BSI (range) | 7 (<1–74) | 58 (21–100) | 8 (<1–36) | |
| Time to ANC >500, n(%) | ||||
| Yes | 1,299 (87) | 824 | 340 | 4,321 (97) |
| No | 188 (13) | 0 | 0 | 138 ( 3) |
| Missing | 5 (<1) | 0 | 0 | 13 (<1) |
| Time to ANC >500 days (range) | 17 (<1–99) | 15 (<1–42) | 16 (1–50) | 15 (<1–111) |
| Platelet engraftment >20 ×109/L, n(%) | ||||
| Yes | 1,103 (74) | 721 (88) | 277 (81) | 4,049 (91) |
| No | 368 (25) | 96 (12) | 57 (17) | 395 ( 9) |
| Missing | 21 ( 1) | 7 (<1) | 6 ( 2) | 28 (<1) |
| Time to platelet >20×109/L, days (range) | 27 (1–180) | 20 (<1–293) | 26 (1–640) | 19 (<1–753) |
| aGVHD, n(%) | ||||
| Yes | 546 (37) | 433 (53) | 195 (57) | 1,673 (37) |
| No | 940 (63) | 387 (47) | 141 (41) | 2,783 (62) |
| Missing | 6 (<1) | 4 (<1) | 4 ( 1) | 16 (<1) |
| Time to aGVHD diagnosis, days (range) | 28 (7–175) | 27 (7–176) | 26 (7–168) | 29 (7–178) |
| Median follow-up of survivors, months (range) | 60 (3–87) | 60 (3–81) | 60 (12–85) | 59 (3–87) |
Abbreviations: aGVHD, acute graft-versus-host disease; ANC, absolute neutrophil count; cGVHD, chronic graft-versus-host disease; VEP, very early phase; LEP, late early phase