Table 1. Identified Antigens in GFBP Valve and Mechanical Valve Patients.

The table shows the protein name, gene name, accesion number and previous literature evidence of antigenicty is cited in the right hand column. The double black line separates the BP antigens that were found to be significant in GFBP valve patients (top) from those in the mechanical valve patients (bottom).

Protein Name	Gene Name	Accession Number	Literature Antigenicity
Alpha-2-macroglobulin receptor-associated protein	LRPAP1	F6RBT3	[17, 18]
Ras-related protein Rab-21	RAB21	Q17R06
26S protease regulatory subunit 6B	PSMC4	Q3T030	[19]
Annexin A11	ANX11	P27214	[20–22]
26S protease regulatory subunit 8	PSMC5	P62194	[23]
Alpha-fetoprotein	AFP	Q3SZ57	[24]
ATP-dependent RNA helicase A	DHX9	Q28141	[25]
60S ribosomal protein L23a	RL23A	Q24JY1	[26]
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	ACADM	Q3SZB4
Apolipoprotein B-100	APOB	E1BNR0	[27, 28, 35]
ARSB protein	ARSB	A6QLZ3	[29]
Proteasome subunit beta type 3	PSMB3	P33672
Epoxide hydrolase 1	EPHX1	Q3ZCJ6	[30, 31]
Coagulation factor XIII A chain	F13A1	F1MW44	[32]
L-lactate dehydrogenase B chain	LDHB	Q5E9B1	[33]
26S proteasome non-ATPase regulatory subunit 3	PSMD3	Q2KJ46	[34]
Pyrroline-5-carboxylate reductase 3	PYCRL	Q58D08
Hyaluronan and proteoglycan link protein 3	HAPLN3	F6QLF1
Calpain-1 catalytic subunit	CAPN1	Q27970
Mannose-1-phosphate guanyltransferase beta	GMPPB	Q2YDJ9
Uncharacterized protein	LOC515150	G3N0S9
Collagen alpha-1(III) chain	COL3A1	F1MXS8	[36]
72 kDa type IV collagenase	MMP2	F1MKH8	[37]
Xanthine dehydrogenase/oxidase	XDH	F1MUT3
Uncharacterized protein	G3MZE0	G3MZE0
Beta-2-microglobulin	B2M	P01888	[38]
D-3-phosphoglycerate dehydrogenase	PHGDH	Q5EAD2	[39]
Uncharacterized protein	LOC525947	E1BI82
Canopy 2 homolog	CNPY2	Q1LZ72
Vitamin K-dependent protein S	PROS1	P07224	[40–42]