Table 4.

Evaluation of the NIPSCCD method in detecting CNVs

CNV size	TP	FP	FN	Sensitivity (%)	PPV (%)	FNR (%)
>10 Mb	11	2	1	91.67	84.62	9.33
5 Mb–10 Mb	5	2	0	100.00	71.43	NA
<5 Mb	13	3	6	68.42	81.25	31.58
Total CNVs	29	7	7	80.56	80.56	19.44

TP, true positive NIPSCCD‐detected CNVs that were confirmed by amniocytes testing; FP, inconsistent CNVs that were detected by NIPSCCD while not detected by amniocytes testing were classified as false positive; FN, amniocytes testing‐characterized CNVs that were not detected by the NIPSCCD method; PPV, positive predictive value; FNR, false negative rate; NA, not applicable.