Figure 5.
miR‐1281 exerted its role through downregulation of TLE1. (a) Significantly higher TLE1 expression in gastric cancer tissues than in their adjacent tissues. (b) TLE1 negatively correlated with miR‐1281 in gastric cancer, p < 0.05, R 2 = 0.4552. (c,d) After upregulation of TLE1 expression in HGC‐27 and SGC‐7901 cells, significantly higher cell proliferation and partial reversion of the suppression of miR‐1281 on cell proliferation. (e) After upregulation of TLE1 expression in SGC‐7901 and HGC‐27 cells, significantly higher cell migration and partial reversion of the suppression of miR‐1281 on cell migration. *p < 0.05, **p < 0.01, ***p < 0.001