Figure 6.

The potency of Cyt-bc₁:aa₃ inhibitors is less affected by glycerol supplementation in recent clinical isolates. The laboratory strain M. tuberculosis H37Rv (red circles), and the recent clinical isolates N0145 (green squares), N0155 (blue triangles), N0153 (purple diamonds), N0157 (pink hexagon) and N0052 (orange stars) were grown in the presence of Q203 at 50X its MIC₅₀ in 7h9 liquid broth medium supplemented (A) or not (B) with 0.2% glycerol. Bacterial growth was recorded over a 15 days period by following the optical density at 600 nm. Each reading was performed in triplicate and results expressed as mean ± SD.