Table 2.
The mean organ/tissue weights ±S.E.M. normalized to tibial length for NCD (±0.01%) CAP and HFD (±CAP)-fed wild type mice.
Organ/tissue (g/cm) | NCD | NCD + 0.01% CAP | HFD | HFD + 0.001% CAP | HFD + 0.003% CAP | HFD + 0.005% CAP | HFD + 0.01% CAP | HFD + 0.03% CAP |
---|---|---|---|---|---|---|---|---|
Heart | 0.11 ± 0.01 | 0.11 ± 0.01 | 0.11 ± 0.004 | 0.10 ± 0.003 | 0.12 ± 0.01 | 0.11 ± 0.01 | 0.09 ± 0.004 | 0.1 ± 0.01 |
Liver | 0.94 ± 0.05 | 0.81 ± 0.06 | 1.21 ± 0.06 | 1.24 ± 0.04 | 0.75 ± 0.05 | 0.79 ± 0.07 | 0.73 ± 0.03 | 0.84 ± 0.04 |
Kidneys | 0.24 ± 0.01 | 0.21 ± 0.02 | 0.28 ± 0.02 | 0.3 ± 0.03 | 0.21 ± 0.01 | 0.19 ± 0.01 | 0.22 ± 0.01 | 0.21 ± 0.02 |
Spleen | 0.05 ± 0.004 | 0.06 ± 0.004 | 0.08 ± 0.004 | 0.085 ± 0.002 | 0.08 ± 0.02 | 0.06 ± 0.01 | 0.05 ± 0.004 | 0.07 ± 0.01 |
Epididymal fat | 0.27 ± 0.03 | 0.25 ± 0.03 | 0.87 ± 0.11 | 0.89 ± 0.14 | 0.76 ± 0.19 | 0.37 ± 0.06 | 0.53 ± 0.07 | 1.12 ± 0.21 |
Inguinal | 0.15 ± 0.01 | 0.16 ± 0.01 | 1.26 ± 0.08 | 1.22 ± 0.02 | 0.46 ± 0.09 | 0.25 ± 0.03 | 0.34 ± 0.05 | 0.45 ± 0.1 |
Brown fat | 0.08 ± 0.01 | 0.11 ± 0.02 | 0.28 ± 0.02 | 0.3 ± 0.03 | 0.25 ± 0.05 | 0.18 ± 0.03 | 0.17 ± 0.04 | 0.25 ± 0.03 |
Retroperitoneal fat | 0.13 ± 0.06 | 0.07 ± 0.01 | 0.65 ± 0.05$$,** | 0.70 ± 0.04$$,** | 0.29 ± 0.07 | 0.18 ± 0.05 | 0.22 ± 0.04 | 0.33 ± 0.08 |
$$Significance for P < 0.01 between NCD and HFD (±0.001% CAP) groups. **Significance for P < 0.01 between HFD (±0.001% CAP) and HFD (±CAP >0.001%) groups.