Table 3.
Clinical chemistry of HFD (±CAP)-fed WT mice.
| Parameters Measured | NCD | HFD | HFD + CAP (%) | ||||
|---|---|---|---|---|---|---|---|
| 0.001 | 0.003 | 0.005 | 0.01 | 0.03 | |||
| Total plasma protein (g/dl) | 4.8 ± 0.33 | 5.3 ± 0.59 | 4.96 ± 0.49 | 4.81 ± 0.22 | 4.91 ± 0.21 | 4.79 ± 0.15 | 4.89 ± 0.05 |
| Alkaline phosphatase (U/L) | 55 ± 7.17 | 55.5 ± 9.07 | 62.66 ± 6.31 | 40 ± 4.42 | 36 ± 3.07 | 40 ± 5.03 | 64 ± 4.13 |
| Alanine aminotransferase (ALT; U/L) | 39 ± 3.64 | 101 ± 10.88$$,** | 98.33 ± 8.56$$,** | 36 ± 2.51 | 39 ± 3.05 | 40.3 ± 4.12 | 35 ± 5.22 |
| Lipase (for acute pancreatitis; U/L) | 125 ± 16.2 | 120 ± 10.11 | 115.88 ± 9.92 | 107.3 ± 15.6 | 96.14 ± 7.11 | 125 ± 5.09 | 96.51 ± 4.91 |
| Creatinine (Kidney function test; mg/dl) | 0.4 ± 0.14 | 1.1 ± 0.26$$,** | 1.01 ± ×0.091$$,** | 0.2 ± 0.05 | 0.2 ± 0.12 | 0.3 ± 0.04 | 0.4 ± 0.03 |
| Blood Urea Nitrogen (BUN; mg/dl) | 33.6 ± 0.72 | 26.2 ± 2.81 | 28.23 ± 1.08 | 23 ± 0.51 | 25 ± 0.05 | 32 ± 0.51 | 25 ± 0.23 |
| WBC count/μL | 7.4 ± 1.3 | 6.1 ± 0.26 | 6.2 ± 0.22 | 6.4 ± 1.24 | 5.9 ± 1.52 | 6.4 ± 1.32 | 6.1 ± 1.57 |
| Hemoglobin (g/dl) | 13.5 ± 1.10 | 14.2 ± 1.52 | 13.88 ± 1.26 | 13.2 ± 1.24 | 13.6 ± 1.56 | 14.2 ± 1.13 | 13.9 ± 1.21 |
| Erythrocytes ×106/μL | 8.64 ± 1.08 | 9.21 ± 1.11 | 8.89 ± 1.01 | 8.43 ± 1.52 | 8.97 ± 1.21 | 9.47 ± 1.04 | 9.2 ± 1.22 |
| Platelets ×103/μL | 797 ± 112 | 722 ± 100 | 766 ± 114 | 711 ± 150 | 714 ± 112 | 736 ± 120 | 725 ± 106 |
$$Significance for P < 0.01 between NCD and HFD (±0.001% CAP) groups.
**Significance for P < 0.01 between HFD (±0.001% CAP) and HFD (±CAP >0.001%) groups.