Table 2.
Differentially abundant proteins for the Interaction term age × oxygen, where p < 0.05 and log2FC > |0.2|.
| Gene | Description | Function | log2FC 90% | log2FC J | p |
|---|---|---|---|---|---|
| EIF5A2 | Eukaryotic translation initiation factor 5A-2 | translation | −0.250 | 0.139 | 0.001 |
| ENO2 | Enolase 2 | glycolysis | 0.307 | −0.490 | 0.002 |
| COPS3 | COP9 signalosome complex subunit 3 | regulates protein degradation | −0.050 | 0.353 | 0.003 |
| SEC.11A | Signal peptidase complex catalytic subunit | removes signal peptides from nascent proteins | 0.207 | −0.081 | 0.005 |
| OVOS | Ovostatin homolog | proteinase inhibitor | −0.275 | 0.293 | 0.006 |
| GDA | Guanine deaminase | purine metabolism | −0.213 | 0.018 | 0.008 |
| SGCB | Beta-sarcoglycan | links muscle cytoskeleton to extracellular matrix | 0.007 | 0.502 | 0.008 |
| PLD3 | Phospholipase D3 | hydrolyzes membrane phopsholipids | 0.132 | −0.323 | 0.008 |
| IGSF9 | Ig superfamily member 9 | cell adhesion | 0.242 | −0.080 | 0.014 |
| TFRC | Transferrin receptor | cellular iron uptake | 0.208 | −0.068 | 0.014 |
| EHD2 | EH domain containing 2 | endocytosis | 0.042 | 0.298 | 0.014 |
| SOD3 | Cu-Zn superoxide dismutase | antioxidant | −0.150 | 0.290 | 0.014 |
| NPPA | Natriuretic peptide A | regulates extracellular fluid volume | 0.248 | −0.293 | 0.015 |
| CD34 | Hematopoietic progenitor cell antigen | cell adhesion | 0.578 | −0.151 | 0.017 |
| PSMB3 | Proteasome subunit beta type-3 | degradation of ubiquitinated proteins | 0.245 | −0.044 | 0.017 |
| ESD | S-formylglutathione hydrolase B | serine hydrolase | −0.252 | 0.069 | 0.017 |
| PYGB | Glycogen phosphorylase | glycogen mobilization | −0.235 | 0.098 | 0.018 |
| MYO1C | Unconventional myosin-lc | intracellular movement | −0.066 | 0.242 | 0.021 |
| TPD52L2 | Tumor protein D54 | cell proliferation | 0.024 | −0.221 | 0.021 |
| THYN1 | Thymocyte nuclear protein | induction of apoptosis | 0.085 | −0.473 | 0.025 |
| VCAN | Versican core protein | cell adhesion | 0.224 | −0.101 | 0.026 |
| DCPS | Decapping scavenger enzyme | mRNA degradation | −0.885 | −0.001 | 0.030 |
| SGCD | Sarcoglycan delta | links muscle cytoskeleton to extracellular matrix | −0.027 | 0.229 | 0.030 |
| GRSF1 | G-rich sequence factor 1 | regulates mitochondrial gene expression | −0.105 | 0.349 | 0.035 |
| CMAS | N-acylneuraminate cytidylyltransferase | sialic acid synthesis | −0.248 | 0.143 | 0.040 |
| ARL6IP5 | PRA1 family protein 3 | regulates intracellular taurine and glutamate | −0.300 | 0.207 | 0.040 |
| CLYBL | Citrate lyase subunit beta | mitochondrial vitamin b12 metabolism | −0.360 | 0.252 | 0.041 |
| NDUFAF6 | NADH:ubiquinone oxidoreductase assembly factor | complex I biosynthesis | 0.011 | −0.215 | 0.044 |
| SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase | innate immune response | −0.101 | −0.314 | 0.047 |
Proteins are listed by increasing p-value, and significant log2FC fields are in bold font. FC = fold change; 90% = 90% incubation; J = juvenile.