Table 2.
List of down-regulated proteins.
| Down-regulated proteins | |||
|---|---|---|---|
| Gene name | Accession Number | Protein description | Ratio (siRNAZIP14 vs. Control siRNA) |
| Dcp1a | D4AE80 | mRNA-decapping enzyme 1A | 0.70 |
| Pdcd11 | D3ZNI3 | Protein RRP5 homolog | 0.72 |
| Pdp2 | A0A0G2JSL7 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial | 0.76 |
| Cfdp1 | A0A0G2K6H5 | Craniofacial development protein 1 | 0.77 |
| Mrps5 | D3ZYT2 | Mitochondrial ribosomal protein S5 | 0.78 |
| Reps2 | A0A0G2K1L4 | RalBP1-associated Eps domain-containing protein 2 | 0.78 |
| Zfp512 | D3ZIF0 | Zinc finger protein 512 | 0.79 |
| Ap2a1 | D3ZUY8 | Adaptor protein complex AP-2, alpha 1 subunit | 0.80 |
| Mki67 | D4A0Y6 | Protein Mki67 | 0.80 |
| Nup205 | D4A7R3 | Nucleoporin 205 kDa | 0.81 |
| Ranbp2 | M0R3M4 | E3 SUMO-protein ligase RanBP2 | 0.81 |
| Pbdc1 | G3V6C3 | Protein Pbdc1 | 0.82 |
| Noc2l | E9PTF3 | Nucleolar complex protein 2 homolog | 0.82 |
| Nop56 | Q4KLK7 | Nucleolar protein 5 A | 0.84 |
| Wdr37 | D3ZQ02 | WD repeat-containing protein 37 | 0.84 |
| Sept3 | F1LMH0 | Neuronal-specific septin-3 | 0.84 |
| Ampd2 | A0A0G2K3U1 | AMP deaminase 2 | 0.85 |
| Tmed4 | B5DEM3 | Transmembrane emp24 domain-containing protein 4 | 0.85 |
| Numa1 | F7FF45 | Nuclear mitotic apparatus protein 1 | 0.85 |
| Aco1 | G3V6S2 | Cytoplasmic aconitate hydratase | 0.85 |
| Slirp | D4A4W6 | SRA stem-loop-interacting RNA-binding protein, mitochondrial | 0.86 |
| Pacs1 | F1LPG3 | Phosphofurin acidic cluster sorting protein 1 | 0.86 |
| Strbp | D3ZDD7 | Spermatid perinuclear RNA binding protein, isoform | 0.87 |
| Hnrnpr | Q566E4 | Heterogeneous nuclear ribonucleoprotein R | 0.87 |
| Osbpl7 | A0A0G2K0D5 | Oxysterol-binding protein | 0.87 |
| Gga3 | A0A0G2JV04 | Protein Gga3 | 0.87 |
| Pfkfb2 | R9PXY6 | 6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2, isoform CRA_a | 0.87 |
| Nop58 | Q5PPK6 | Nucleolar protein 58 | 0.88 |
List of the 28 proteins that were down-regulated in Zip14 siRNA- vs. non-targeting siRNA-treated (Control siRNA) cells. Proteins with a fold change >1.136 or <0.88, and a false discovery rate <0.05, were included. Gene name, accession number, and ratio are listed, together with a short description (from uni-prot.org, using the descriptions from the human database, when not available for Rattus norvegicus).