Table 3.
List of up-regulated proteins.
| Up-regulated proteins | |||
|---|---|---|---|
| Gene name | Accession | Protein description | Ratio (siRNAZIP14 vs. Control siRNA) |
| Itln1 | Q499T8 | Intelectin 1 (Galactofuranose binding) | 1.15 |
| Rpl22l1 | B2RZD5 | 60S ribosomal protein L22-like 1 | 1.15 |
| Dera | F1M1H0 | Deoxyribose-phosphate aldolase | 1.16 |
| Gba | B2RYC9 | Glucosylceramidase | 1.16 |
| LOC681282 | D3ZDG0 | Unknown | 1.16 |
| Vgf | F1LP80 | Neurosecretory protein VGF | 1.16 |
| Rnf213 | F1M0R1 | E3 ubiquitin-protein ligase RNF213 | 1.17 |
| Rab3b | Q6P9W6 | Ras-related protein Rab-3B | 1.18 |
| Adpgk | G3V784 | ADP-dependent glucokinase, isoform CRA_a | 1.18 |
| Srrm2 | A0A0G2K2M9 | Serine/arginine repetitive matrix protein 2 | 1.18 |
| Evi5 | D3ZJN9 | Ecotropic viral integration site 5 protein | 1.18 |
| Chga | F8QYX0 | Chromogranin A | 1.18 |
| Rfc2 | Q9QXI2 | Replication factor C subunit 2 (Fragment) | 1.18 |
| Tspan6 | B0BN20 | Tetraspanin | 1.19 |
| Camk2b | F1LNI8 | Calcium/calmodulin-dependent protein kinase type II subunit beta | 1.20 |
| Tgfbi | D4A8G5 | Transforming growth factor-beta-induced protein ig-h3 | 1.22 |
| Cdk12 | A0A0G2K5U7 | Cyclin-dependent kinase 12 | 1.23 |
| RGD1560212* | A0JPQ5 | N-alpha acetyltransferase 11 (88.6% homologue) | 1.23 |
| Edem3 | D4AB70 | alpha-1,2-Mannosidase | 1.24 |
| Wnk3 | A0A0G2K2Y2 | Serine/threonine-protein kinase WNK3 | 1.25 |
| Cnn2 | D3ZRX9 | Calponin | 1.26 |
| Resp18 | A0A0G2JZD6 | Regulated endocrine-specific protein 18 | 1.37 |
| Reep1 | D4A193 | Receptor expression-enhancing protein | 1.39 |
| Muc13 | F1M9I3 | Mucin-13 | 2.45 |
List of the 24 proteins that were up-regulated in Zip14 siRNA- vs. non-targeting siRNA-treated (Control siRNA) cells. Proteins with a fold change >1.136 or <0.88, and a false discovery rate <0.05, were included. Gene name, accession number, and ratio are listed, together with a short description (from uni-prot.org, using the descriptions from the human database, when not available for Rattus norvegicus). *Analyzed by the Blast function of uni-prot.org. RGD1560212 showed 88.6% homology with Mus musculus N-alpha acetyltransferase 11.