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. 2019 May 14;6:100033. doi: 10.1016/j.ynpai.2019.100033

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 2 — CCI increases mechanical sensitivity (allodynia) and facial grimace scores. A. Mechanical sensitivity thresholds pre & post injury. Repeated measures analysis showed that CCI-ION injury resulted in allodynia or mechanical hypersensitivity, shown by a significant decrease in von Frey thresholds (F_1,31 = 95.713; p < 0.001). There was no difference across groups (F_3,31 = 0.897; p = 0.454). B. The graph shows that CCI-ION injury resulted in a significant in increase in RGS (F_1,31 = 26.561; p < 0.001). Similar to the test for allodynia, there was no significant difference across groups (F_3,31 = 1.099; p = 0.364). Data are reported as scatterplots with means and 95% CI, showing individual animal scores. (n = 35).