Table 4.
Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in adenocarcinomas (n = 28)
| Partial response (n = 16) | Stable disease (n = 9) | Progressive disease (n = 3) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline | Control | p value | Baseline | Control | p value | Baseline | Control | p value | |
| Blood flow (mL/100 mL/min) | 157.7 ± 87.6 | 139.9 ± 85.0 | 0.467 | 240.3 ± 274.0 | 192.1 ± 115.8 | 0.639 | 171.7 ± 146.2 | 170.4 ± 130.3 | 0.968 |
| Blood volume (mL/100 mL) | 7.5 ± 3.3 | 6.8 ± 3.0 | 0.397 | 9.0 ± 4.9 | 7.9 ± 2.8 | 0.572 | 7.3 ± 2.8 | 7.3 ± 4.8 | 0.975 |
| Permeability (mL/100 mL/min) | 15.3 ± 5.6 | 15.1 ± 7.7 | 0.913 | 20.2 ± 13.9 | 16.6 ± 6.1 | 0.491 | 18.3 ± 6.5 | 17.7 ± 9.6 | 0.809 |
| Mean transit time (s) | 6.7 ± 3.25 | 6.4 ± 2.3 | 0.710 | 6.3 ± 1.6 | 5.8 ± 2.0 | 0.350 | 7.8 ± 3.5 | 7.0 ± 3.6 | 0.465 |
| RECIST-1.1 diameter (mm) | 58.1 ± 25.3 | 41.4 ± 19.3 | 0.00 | 54.2 ± 25.0 | 51 ± 24.92 | 0.041 | 58.7 ± 20.4 | 65.0 ± 26.2 | 0.210 |
| Tumour volume (cc) | 99.6 ± 163.9 | 35.7 ± 62.9 | 0.051 | 125.0 ± 168.4 | 96.6 ± 150.0 | 0.137 | 93.3 ± 73.4 | 126.7 ± 97.6 | 0.145 |
Significant p values are in bold
RECIST Response evaluation criteria in solid tumours