Table 5.
Changes in perfusion parameters, RECIST-1.1 diameter, and tumour volume in epidermoid carcinomas (n = 16)
| Partial response (n = 10) | Stable disease (n = 6) | |||||
|---|---|---|---|---|---|---|
| Baseline | Control | p value | Baseline | Control | p value | |
|
Blood flow (mL/100 mL/min) |
176.1 ± 76.1 | 186.5 ± 106.4 | 0.775 | 234.9 ± 97.5 | 165.8 ± 108.7 | 0.010 |
| Blood volume (mL/100 mL) | 8.6 ± 3.3 | 5.9 ± 2.6 | 0.007 | 6.4 ± 2.8 | 5.2 ± 3.4 | 0.269 |
| Permeability (mL/100 mL/min) | 15.9 ± 6.9 | 11.1 ± 7.0 | 0.062 | 16.5 ± 11.5 | 6.7 ± 4.1 | 0.036 |
| Mean transit time (s) | 7.5 ± 3.6 | 5.3 ± 2.7 | 0.018 | 3.6 ± 1.7 | 5.3 ± 2.9 | 0.267 |
| RECIST-1.1 diameter (mm) | 54.5 ± 21.4 | 35.7 ± 15.7 | 0.002 | 62.5 ± 24.3 | 59.8 ± 23.9 | 0.082 |
| Tumour volume (cc) | 142.5 ± 171.8 | 56.1 ± 62.6 | 0.038 | 57.0 ± 4.6 | 22.5 ± 18.9 | 0.021 |
RECIST Response evaluation criteria in solid tumours
Significant p values are in bold