. 2018 Apr 15;465:4–26. doi: 10.1016/j.mce.2017.08.016

Table 2.

Serum concentrations of C₁₉steroids determined by liquid chromatography tandem mass spectrometry. All concentrations are shown in nmol/L except for DHEA sulfate (DHEAS), which are shown in the micromolar range. The details of the original studies are given in the footnotes below the table.

Androgen precursors	Women	Men	Androgen metabolites	Women	Men
DHEA	4.2–11.8^a	6.9–30^c	Androsterone (AST)	0.4–2.1^c	0.9–1.9^c
	6.3–35.4^c	15.8^g	Androsterone (AST)	0.5 ± 0.03^d	0.7 ± 0.03^d
	3.4 ± 0.03^d	4.1 ± 0.1^d	AST-sulfate	nd^d	19 ± 1.6^d
		10–20^j	AST-sulfate		1250–2500^j
DHEA sulfate	3400–9600^a	1312–14125^c	AST-glucuronide	28–467^c	59–248^c
	701–8965^c	5709^g		89 ± 0.7^d	104 ± 1.4^d
	3337 ± 16^d	3247 ± 50^d		2.1–170^e	86–150^h
		4300–5400^j	EpiAST	0.6 ± 0.03^d	0.3 ± 0.02^d
A4	3.3–9.2^a	2.3–5.5^c	EpiAST-sulfate	123±3^d	105 ± 3.2^d
	1.2–2.82^b	3.64^g	EpiAST-sulfate		500–850^j
	1.1–8.7^c		EpiAST-glucuronide	78 ± 0.4^d	76 ± 1.3^d
5-androstenediol (5-diol)	1.5 ± 0.07^d	1.7 ± 0.2^d	3α-androstanediol (3α-adiol)	nq^d	0.2 ± 0.02^d
5-diol-sulfate	215 ± 21^d	178 ± 10^d	3α-adiol-sulfate	nd^d	nd^d
5-diol-sulfate		250–500^j	3α-adiol-3-glucuronide	0.6–8.4^c	1.3–6.7^c
5α-androstanedione	0.5–2.6^c	1.0–1.5^c	3α-adiol-3-glucuronide	0.5–9.2^e	2.0–3.8^h
11OHA4	4.9–12.5^a	2.3–5.1ⁱ	3α-adiol-17-glucuronide	0.3–10^c	6.2–8.8^c
11KA4	2–3.9^a	0.7–1.4ⁱ		0.5–12^e	5.4–11^h
11OHT	0.1–0.3^a	0.3–0.7ⁱ	DHEA-glucuronide	0.9 ± 0.001^d	0.7 ± 0.03^d
11OHT			7αOH-DHEA	0.08–1.4^f
Active Androgens			7βOH-DHEA	0.08–0.9^f
T	0.2–0.5^a	7.4–14^c	7-oxo-DHEA	0.03–0.6^f
	0.58–1.1^b	16.85^g	16OH-DHEA-sulfate		100–200^j
	0.4–4.1^c	15.6 ± 0.6^d	T-sulfate	nd^d	nd^d
	1.1 ± 0.09^d	10–20^j	T-glucuronide	0.8 ± 0.02^d	26.5 ± 0.1^d
Calculated free T	0.0056–0.0122^b	0.3780^g	DHT-sulfate	0.3–2.7^c	2.5–3.5^c
DHT	0.2–0.9^c	0.9–2^c	DHT-sulfate	nd^d	nd^d
DHT	0.4–0.01^d	1.2 ± 0.09^d	DHT-glucuronide	nd^d	nd^d
11KT	1.2–1.8^a	1.0–2.6ⁱ	5-diol-glucuronide	nq^d	nq^d

O'Reilly et al. (2016), interquartile range, n = 49, age interquartile range 23–32.

Haring et al. (2012), interquartile range, n = 985, age 20-80.

Trabert et al. (2016), min-max, pre- and postmenopausal women, n = 15.

Zang et al. (2017), mean ± standard deviation for triplicate of pooled commercial serum.

Labrie et al. (2006), min-max, pre- and postmenopausal women, n = 424.

Ke et al. (2016), min-max, pre- and postmenopausal women, n = 34.

Damgaard-Olesen et al. (2016), geometric mean, n = 72, age 30-<40.

Vandenput et al. (2007), interquartile range, n = 1086, age interquartile range 18.4–19.3.

ⁱ

Turcu et al. (2016), interquartile range, combined values for 19 men and 19 women, age 3-59.

Sanchez-Guijo et al. (2016), interquartile range estimated from Fig. 2, n = 60, age range 18–60.