FIGURE 1.

Ovalbumin (OVA)-induced acute model of asthma. (A) Pulmonary inflammatory response was increased in the mice challenged with OVA, bar = 20 μm. (B) The airway hyperresponse was elevated in the mice from the asthma group, ^∗p < 0.05 (C). Sera IgE was significantly increased in the mice from the asthma group, ^∗p < 0.05. (D) CD4⁺ T cells magnificently sorted from the spleen were validated by flow cytometry. Representative results of two independent experiments with five mice in each group, ^∗∗p < 0.01, ^∗∗∗p < 0.01, ^∗∗∗∗p < 0.0001.