Table 3.
GRADE analyses: prospective memory in non-psychotic first-degree relatives of patients with schizophrenia
| Meta-analytic outcomes | Studies (N) | Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | Large effect | Overall quality of evidencea |
|---|---|---|---|---|---|---|---|---|
| Overall PM | 2 (127) | No | No | No | No | Seriousb | No | +/+/±/;Moderate |
| Time-based PM | 4 (268) | No | No | No | No | Seriousb | No | +/+/±/;Moderate |
| Event-based PM Activity-based PM |
4 (268) 2 (127) |
No No |
No No |
No No |
No No |
Seriousb Seriousb |
No No |
+/+/±/;Moderate +/+/±/;Moderate |
Notes: aGRADE Working Group grades of evidence: High quality=further research is very unlikely to change our confidence in the estimate of effect. Moderate quality=further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. Low quality=further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. Very low quality=we are very uncertain about the estimate. bFor continuous outcomes, N<400.
Abbreviations: GRADE, grading of recommendations assessment, development, and evaluation; PM, prospective memory.