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. 2019 May 24;18(1):509–516. doi: 10.3892/etm.2019.7612

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — LBP downregulates inflammatory cytokine production in STZ-induced diabetic rats. Serum (A) IL-6 and (B) TNF-α content in STZ-induced rats. The expression of (C) IL-6, (D) TNF-α, (E) ICAM-1, (F) VCAM-1 and (G) TLR-4 as determined via western blotting. Data are expressed as the mean ± SEM (A and B, n=10; C-G, n=4). *P<0.05. LBP, lycium barbarum polysaccharide; STZ, streptozotocin; IL-6, interleukin-6; TNF-α, tumor necrosis factor-α; ICAM-1, intercellular adhesion molecule-1; VCAM-1, vascular adhesion molecule-1; TLR-4, Toll like receptor-4.