Table I.
Body weight (g) | Blood glucose concentration (mmol/l) | |||||
---|---|---|---|---|---|---|
Group | Prior to STZ injection | 2 days post-STZ injection | 6 weeks post-STZ injection | Prior to STZ injection | 2 days post-STZ injection | 6 weeks post-STZ injection |
Control | 133.27±3.67 | 141.59±4.92 | 404.85±31.48 | 5.71±0.55 | 6.25±0.64 | 5.67±0.43 |
Diabetes | 134.16±4.03 | 142.02±5.63 | 299.26±47.14a | 5.64±0.66 | 21.87±3.35a | 25.07±2.59a |
L-TSIIA | 136.40±4.23 | 144.20±5.51 | 311.99±49.92a | 6.12±0.79 | 21.78±4.73a | 20.78±2.88a,b |
H-TSIIA | 130.08±5.39 | 138.68±6.55 | 289.50±42.18a | 5.68±0.52 | 23.89±4.18a | 23.46±3.05a |
Data are presented as the mean ± standard deviation (n=10).
P<0.01 vs. control group
P<0.05 vs. diabetes group. TSIIA, Tanshinone IIA; STZ, streptozotocin; Diabetes, STZ-induced diabetic rats; L-TSIIA, diabetic rat treated with low dose TSIIA (2 mg/kg/day); H-TSIIA, diabetic rat treated with high dose TSIIA (4 mg/kg/day).