Table III.
Kyoto Encyclopedia of Genes and Genomes pathway analysis of miR-183 target genes.
| No. | Pathway description | False discovery rate | Matching proteins in network |
|---|---|---|---|
| 1 | Dopaminergic synapse | 0.0171 | GNG5, PLCB4, PPP2CA, PPP2CB, PPP2R2A, PPP2R5C, PRKCA |
| 2 | Adrenergic signaling in cardiomyocytes | 0.0186 | ATP2B4, PLCB4, PPP2CA, PPP2CB, PPP2R2A, PPP2R5C, PRKCA |
| 3 | Regulation of actin cytoskeleton | 0.0186 | CFL2, ENAH, EZR, FGF9, PFN2, TIAM1, TMSB4X, TMSB4Y |
| 4 | Gastric acid secretion | 0.0186 | EZR, KCNK10, KCNK2, PLCB4, PRKCA |
| 5 | AMPK signaling pathway | 0.0214 | FOXO1, PPP2CA, PPP2CB, PPP2R2A, PPP2R5C, TSC1 |
| 6 | MAPK signaling pathway | 0.0428 | CACNA1E, DUSP10, FGF9, MAP3K4, MAPK8IP1, MEF2C, PRKCA, RPS6KA3 |
| 7 | Long-term depression | 0.0473 | PLCB4, PPP2CA, PPP2CB, PRKCA |
miR, micro-RNA. AMPK, AMP-activated protein kinase; MAPK, mitogen-activated protein kinase.