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. 2019 May 23;18(1):475–482. doi: 10.3892/etm.2019.7600

Figure 4.

Figure 4.

Overexpression of miR-485-3p inhibits glioblastoma cell growth through repression of RNF135. (A) Representative images and quantification from western blot analysis. Transfection with miR-485-3p mimic reduced RNF135 protein expression, while transfection with a RNF135-expressing plasmid reversed this effect in U251-MG cells. (B) Overexpression of miR-485-3p inhibited cell proliferation while transfection of recombinant RNF135 partially recovered cell growth in U251-MG cells. **P<0.01; ***P<0.001, with comparisons indicated by lines. miR, microRNA; RNF135, ring finger protein 135.