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. 2019 May 23;18(1):475–482. doi: 10.3892/etm.2019.7600

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Overexpression of miR-485-3p inhibits glioblastoma cell migration through repression of RNF135. (A) Micrographs captured at 0 and 20 h of the wound-healing assay (magnification, ×100). Overexpression of miR-485-3p inhibited cell migration whilst transfection of recombinant RNF135 reversed cell migration inhibition in U251-MG cells. (B) Quantification of relative wound closure area. ***P<0.001, with comparisons indicated by lines. miR, microRNA; RNF135, ring finger protein 135.