Positive effects of UCA1 on ICC cell proliferation and invasion. (A) UCA1 is downregulated in 9810 cells transfected with UCA1 siRNA compared with that in cells transfected with NC siRNA. (B) The proliferation and (C) invasion of 9810 cells in the UCA1 siRNA group were downregulated compared with those in the NC siRNA group. Magnification, ×200. (D) UCA1 was upregulated in 9810 cells transfected with UCA1 expression plasmid compared with that in cells transfected with blank vector. (E) The proliferation and (F) invasion of 9810 cells were upregulated in the UCA1 group compared with those in the blank group. Magnification, ×200. **P<0.01 vs. NC siRNA or blank. UCA1, urothelial carcinoma-associated 1; ICC, intrahepatic cholangiocarcinoma; siRNA, small interfering RNA; NC, negative control; OD, optical density.