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. 2019 Apr 24;18(1):389–396. doi: 10.3892/etm.2019.7527

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Copyright: © Fei et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — miR-18 inhibits the PI3K/AKT pathway in islet β-cells. (A) miR-18 mimics cause a marked decrease of p-AKT/AKT and p-PI3K/PI3K in MIN6 cells. (B) miR-18 knockdown caused a significant upregulation of levels of-AKT/AKT and p-PI3K/PI3K in MIN6 cells. *P<0.05. miR, microRNA; p-PI3K, phosphorylated phosphoinositide 3-kinase; NC, negative control.