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. 2019 May 7;18(1):77–84. doi: 10.3892/etm.2019.7552

Figure 5.

Figure 5.

Effect of miR-15b on the expression of IGF1R in hVSMCs. hVSMCs were transfected with control-plasmids or IGF1R-plasmids for 48 h. Subsequently, the (A) protein and (B) mRNA levels of IGF1R were determined via western blotting and RT-qPCR, respectively. hVSMCs were also transfected with mimic controls, miR-15b mimics or miR-15b mimic+IGF1R-plasmids for 48 h, following which the (C) protein and (D) mRNA levels of IGF1R were determined via western blotting and RT-qPCR, respectively. All data are presented as the mean ± standard deviation. **P<0.01 vs. the control or mimic control; ##P<0.01 vs. the mimic. miR, microRNA; IGF1R, insulin growth factor 1 receptor; hVSMCs, human vascular smooth muscle cells; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.