Table II.
Brain areas with significantly different ALFF values between groups.
| MNI coordinates | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Comparison of ALFF | L/R | Brain region | X | Y | Z | BA | Peak voxels | T-value | P-values |
| UDs<HCs | |||||||||
| 1 | L | Cerebellar anterior lobe | −36 | −51 | −27 | / | 61 | −5.35 | P<0.001 |
| 2 | R | Middle frontal gyrus | 30 | −6 | 54 | 6 | 19 | −4.5773 | P<0.001 |
| 3 | L | Middle frontal gyrus | −24 | −9 | 51 | 6 | 18 | −4.1103 | P<0.001 |
| UDs>HCs | |||||||||
| 1 | R | Cerebellar inferior lobe | 21 | −69 | −60 | / | 94 | 5.557 | P<0.001 |
| 2 | L | Cerebellar inferior lobe | −36 | −72 | −57 | / | 218 | 5.786 | P<0.001 |
| 3 | L | Inferior temporal gyrus | −57 | −48 | −27 | 20 | 24 | 4.4602 | P<0.001 |
| 4 | R | Fusiform gyrus | 51 | −36 | −27 | 18 | 16 | 4.4716 | P<0.001 |
| 5 | L | Superior frontal gyrus | −18 | 57 | 3 | 9 | 25 | 4.8905 | P<0.001 |
| 6 | R | Angular gyrus | 48 | −63 | 39 | 39 | 16 | 5.2397 | P<0.001 |
| 7 | B | Superior frontal gyrus | 0 | −21 | 78 | 6 | 132 | 4.8908 | P<0.001 |
An independent-samples t-test was applied to obtain P-values for comparisons between CUs and HCs. ALFF, amplitude of low-frequency fluctuation; BA, Brodmann area; CU, corneal ulcer; HCs, healthy controls; MNI, Montreal Neurological Institute; L, left; R, right; B, bilateral; /, brain areas have no clear BA division.