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. 2019 Jun 7;9:472. doi: 10.3389/fonc.2019.00472

Table 1.

AGREE II domains and items (9).

DOMAIN 1. SCOPE AND PURPOSE
Item 1: the overall objective(s) of the guideline is (are) specifically described
Item 2: the health question(s) covered by the guideline is (are) specifically described
Item 3: the population (patients, public, etc.) to whom the guideline is meant to apply is specifically described
DOMAIN 2. STAKEHOLDER INVOLVEMENT
Item 4: the guideline development group includes individuals from all the relevant professional groups
Item 5: the views and preferences of the target population (patients, public, etc.) have been sought
Item 6: the target users of the guideline are clearly defined
DOMAIN 3. RIGOR OF DEVELOPMENT
Item 7: systematic methods were used to search for evidence
Item 8: the criteria for selecting the evidence are clearly described
Item 9: the strengths and limitations of the body of evidence are clearly described
Item 10: the methods for formulating the recommendations are clearly described
Item 11: the health benefits, side effects, and risks have been considered in formulating the recommendations
Item 12: there is an explicit link between the recommendations and the supporting evidence
Item 13: the guideline has been externally reviewed by experts prior to its publication
Item 14: a procedure for updating the guideline is provided
DOMAIN 4. CLARITY OF PRESENTATION
Item 15: the recommendations are specific and unambiguous
Item 16: the different options for management of the condition or health issue are clearly presented
Item 17: key recommendations are easily identifiable
DOMAIN 5. APPLICABILITY
Item 18: the guideline describes facilitators and barriers to its application
Item 19: the guideline provides advice and/or tools on how the recommendations can be put into practice
Item 20: the potential resource implications of applying the recommendations have been considered
Item 21: the guideline presents monitoring and/or auditing criteria
DOMAIN 6. EDITORIAL INDEPENDENCE
Item 22: the views of the funding body have not influenced the content of the guideline
Item 23: competing interests of guideline development group members have been recorded and addressed