Table 3.
Baseline and final values of lipids and apolipoproteins by group allocation.
| Baseline | One Month | Three Months | p Group | p Time | p Interaction | |
|---|---|---|---|---|---|---|
| Total cholesterol, mmol/L | ||||||
| Nutraceutical | 6.07 (5.83 to 6.32) a | 5.38 (5.12 to 5.64) b | 5.22 (5.58 to 6.08) b | 0.326 | <0.001 | <0.001 |
| Placebo | 5.83 (5.58 to 6.08) | 5.66 (5.40 to 5.92) | 5.66 (5.38 to 5.94) | |||
| LDL-cholesterol, mmol/L | ||||||
| Nutraceutical | 3.90 (3.68 to 4.14) a | 3.32 (3.10 to 3.54) b | 3.13 (2.92 to 3.35) b | 0.192 | <0.001 | <0.001 |
| Placebo | 3.71 (3.47 to 3.94) | 3.56 (3.34 to 3.78) | 3.59 (3.38 to 3.78) | |||
| HDL-cholesterol, mmol/L | ||||||
| Nutraceutical | 1.44 (1.26 to 1.62) | 1.47 (1.30 to 1.63) | 1.49 (1.31 to 1.66) | 0.432 | 0.933 | 0.337 |
| Placebo | 1.57 (1.40 to 1.75) | 1.55 (1.39 to 1.72) | 1.54 (1.37 to 1.72) | |||
| Triglycerides, mmol/L | ||||||
| Nutraceutical | 1.53 (1.19 to 1.86) | 1.29 (1.08 to 1.50) | 1.35 (1.11 to 1.60) | 0.251 | 0.058 | 0.507 |
| Placebo | 1.26 (0.92 to 1.60) | 1.19 (0.97 to 1.39) | 1.13 (0.89 to 1.38) | |||
| Non-HDL-cholesterol, mmol/L | ||||||
| Nutraceutical | 4.63 (4.37 to 4.90) a | 3.91 (3.63 to 4.19) b | 3.73 (3.47 to 3.99) b | 0.691 | <0.001 | <0.001 |
| Placebo | 4.26 (3.99 to 4.53) | 4.10 (3.83 to 4.38) | 4.11 (3.85 to 4.38) | |||
| Apo B, mg/dL | ||||||
| Nutraceutical | 116.8 (110.4 to 123.2) a | 102.3 (94.8 to 109.8) b | 101.0 (94.6 to 107.4) b | 0.909 | <0.001 | <0.001 |
| Placebo | 108.3 (101.9 to 114.7) | 105.1 (97.6 to 112.7) | 105.1 (98.7 to 111.5) | |||
| Apo A1, mg/dL | ||||||
| Nutraceutical | 154.4 (144.0 to 164.7) | 160.3 (149.9 to 170.6) | 160.3 (149.5 to 171.0) | 0.251 | 0.226 | 0.338 |
| Placebo | 157.1 (146.8 to 167.5) | 157.8 (147.5 to 168.2) | 157.4 (146.6 to 168.1) |
Values are means (SD). LDL: low-density lipoprotein; HDL: high-density lipoprotein; Apo B: apolipoprotein B; Apo A1: apolipoprotein A1. p value for one-way repeated-measures ANOVA for continuous variables (Group = treatment allocation; Time = baseline, one month, three months), a,b Different superscript letters in the same row mean that values were significantly different, p < 0.05, by ANOVA simple effect analyses with Bonferroni correction.