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. 2019 Jun 7;10:579. doi: 10.3389/fneur.2019.00579

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Copyright © 2019 Wei, Chen, Wu, Lee, Liu, Shyu and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Stroke in different types of cancer. Frequencies of patients with both cancer and stroke were ranked in (A). When patients with stroke were encountered with suspected coexisting cancer, lung cancer, colorectal cancer, and hepatocellular carcinoma should be considered first because of their relatively high frequencies. In individual cancers, certain cancers presented with a relatively high ratio of codeveloping stroke, such as malignant brain tumor, gastric cancer, and prostate cancer (B). The intervals between developing cancer and stroke were also different among cancers (C). Preceding strokes in esophageal cancer and following strokes in nasopharyngeal cancer and ovarian cancer should be considered; otherwise most strokes developed within ± 0.5 years of cancer detection, with a mean interval of −0.4 ± 3.0 years. Abbreviations: ca, cancer; HCC, hepatocellular carcinoma; NPC, nasopharyngeal cancer.