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. 2019 Jun 7;10:579. doi: 10.3389/fneur.2019.00579

Table 1.

Age, sex, and comorbidities of patients with both cancer and stroke, cancer only, and stroke only.

ICD9-CM At cancer diagnosis At stroke onset
Both cancer and stroke Cancer-only p-value Both cancer and stroke Stroke-only p-value
(N = 1877) (N = 26446) (N = 1877) (N = 19689)
Age, year 70.5 ± 13.4 61.1 ± 15.4 <0.0001* 70.1 ± 13.2 67.3 ± 14.8 <0.0001*
Sex (male) 1203 (64.1 %) 14299 (54.1 %) <0.0001* 1203 (64.1 %) 11249 (57.1 %) <0.0001*
COMORBIDITY
Hypertension 401,405 1531 (81.6 %) 13098 (49.5 %) <0.0001* 1531 (81.6 %) 16895 (85.8 %) <0.0001*
Diabetes mellitus 250 905 (48.2 %) 7849 (29.7 %) <0.0001* 905 (48.2 %) 9655 (49.0 %) 0.496
Chronic kidney disease 585 282 (15.0 %) 2085 (7.9 %) <0.0001* 282 (15.0 %) 2748 (14.0 %) 0.204
Atrial fibrillation 427.31 258 (13.8 %) 959 (3.6 %) <0.0001* 258 (13.8 %) 2803 (14.2 %) 0.580
Coronary artery disease 413, 414.0 634 (33.8 %) 4826 (18.3 %) <0.0001* 634 (33.8 %) 7047 (35.8 %) 0.082
Heart failure 428 441 (23.5 %) 2647 (10.0 %) <0.0001* 441 (23.5 %) 4909 (24.9 %) 0.168
Hyperlipidemia 272 924 (49.2 %) 9273 (35.1 %) <0.0001* 924 (49.2 %) 11055 (56.2 %) <0.0001*
COPD 491, 492, 496 815 (43.42%) 7049 (26.65%) <0.0001* 815 (43.42%) 7408 (37.63%) <0.0001*
Alcohol overuse V113, 305.0,303, 291, 357.5, 425.5, 571.0, 571.1, 571.2, 571.3, 980.0 78 (4.16%) 1070 (4.05%) 0.816 78(4.16%) 667(3.39%) 0.082
STROKE CLASSIFICATION
SAH 430 30 (1.6 %) 723 (3.7 %) <0.0001*
ICH 431 286 (15.2 %) 3208 (16.3 %) 0.235
AIS 433, 434 1179 (62.8 %) 11975 (60.8 %) 0.091
TIA 435 274 (14.6 %) 2955 (15.0 %) 0.659
*

p < 0.05 was statistically significant. COPD, chronic obstructive pulmonary disease; SAH, subarachnoid hemorrhage; ICH, intracerebral hemorrhage; AIS, acute ischemic stroke; TIA, transient ischemic attack.