CLD |
Chronic Liver Disease |
ECM |
Extracellular Matrix |
HSCs |
Hepatic Stellate Cells |
DNA |
Deoxyribonucleic Acid |
PTM |
Postranslational Modifications |
HCC |
Hepatocellular Carcinoma |
CpG |
Cytosine Guanine Dinucleotide |
MeCP2 |
Methyl-CpG-Binding Domain Protein 2 |
MBD1-4 |
Methyl-CpG-Binding Domain Protein 1-4 |
DNMTs |
DNA-Methyltransferases |
5mC |
5-Methylcytosine |
5hmC |
5-Hydroxymethylcytosine |
TETs |
Ten Eleven Translocation Enzymes |
APC |
Adenomatous Polyposis Coli Protein |
Wnt5a |
Wnt Family Member 5A |
ACTG |
Actin, Gamma-Enteric Smooth Muscle |
LOXL |
Lysyl Oxidase Like |
Col4a |
Collagen Type IV Alpha |
ADAMTs |
ADAM Metallopeptidase with Thrombospondin Type 1 Motif |
MMP |
Matrix Metalloproteinase |
TGFβR |
Transforming Growth Factor Beta Receptor |
PTEN |
Fosfatidilinositol-3,4,5-Trisfosfato 3-Fosfatasa |
HATs |
Histone Acetyltransferases |
HDACs |
Hisone Deacetylases |
HMTs |
Histone Methyltransferases |
HDMTs |
Hisone Demethylases |
α-SMA |
Alpha Smooth Muscle Actin |
CTGF |
Connective Tissue Growth Factor |
CXCL12 |
C-X-C Motif Chemokine 12 |
IL |
Interleukin |
PDGFA |
Platelet Derived Growth Factor Subunit A |
VEGFA |
Vascular Endothelial Growth Factor A |
SIRT |
Seven Sirtuin Proteins |
mRNA |
Messenger Ribonucleic Acid |
HGF |
Hepatocyte Growth Factor |
TSA |
Trichostatin A |
ERK |
Extracellular Signal–Regulated Kinases |
PI3K |
Phosphatidylinositol-3- Kinase |
MLL |
Mixed Lineage Leukemia Protein |
MEF |
Mouse Embryonic Fibroblast |
COMPASS |
Complex Proteins Associated with Set1 |
ASH2 |
Set1/Ash2 Histone Methyltransferase complex subunit ASH2 |
SET1 |
Histone-lysine N-methyltransferase SETD1A |
TIMP |
Tissue Inhibitors of Metalloproteinases |
EZH2 |
Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit |
PCR2 |
Polycomb Repressive Complex 2 |
PDGF-BB |
Platelet-Derived Growth Factor-BB |
PPARɣ |
Peroxisome Proliferator-Activated Receptor Gamma |
JMJD |
Jumonji Domain-Containing Protein |
KDM4D |
Lysine Demethylase 4D |
HP1 |
Heterochromatin Protein 1 |
NAFLD |
Non-Alcoholic Fatty Liver Disease |
ALD |
Alcoholic Liver Disease |
NASH |
Non-Alcoholic Steatohepatitis |
SAHA |
Suberoy- Lanilide Hydroxamic Acid |
DZNep |
3-Deazaneplanocin A hydrochloride |
ScAb |
Single-Chain Antibody |