Table 3.
Multivariable logistic regression analyses for signs and symptoms of liver disease in patients infected with hepatitis C virus, n=755. Values are odds ratio (95% confidence intervals)
| Factor/levels | Mild or severe infection v no infection
|
Severe infection v no or mild infection
|
|||
|---|---|---|---|---|---|
| Odds ratio | P value | Odds ratio | P value | ||
| Sex: | |||||
| Male | 1 | 0.11 | 1 | 0.019 | |
| Female | 0.69 (0.44 to 1.10) | 0.38 (0.17 to 0.88) | |||
| Alcohol consumed (units/week): | |||||
| <20 | 1 | 0.13 | 1 | 0.14 | |
| None | 1.20 (0.70 to 2.06) | 1.97 (0.77 to 5.07) | |||
| ⩾20 | 1.97 (1.10 to 3.51) | 2.84 (1.09 to 7.41) | |||
| Unknown | 0.93 (0.37 to 2.36) | 1.19 (0.23 to 6.16) | |||
| Age at transfusion (years): | |||||
| 0-19 | 1 | 0.028 | 1 | 0.24 | |
| 20-39 | 1.15 (0.53 to 2.51) | 2.19 (0.50 to 9.63) | |||
| 40-49 | 1.96 (0.86 to 4.53) | 4.48 (1.00 to 20.08) | |||
| 50-59 | 2.76 (1.27 to 6.03) | 3.52 (0.79 to 15.42) | |||
| ⩾60 | 1.38 (0.65 to 2.95) | 3.22 (0.79 to 13.06) | |||
| Time since transfusion | |||||
| Years | 1.096 (1.00 to 1.20) | 0.045 | 1.098 (0.95 to 1.26) | 0.22 | |
| HCV ribonucleic acid status: | |||||
| No | 1 | <0.001 | 1 | 0.008 | |
| Yes | 6.44 (2.67 to 15.48) | 4.18 (0.94 to 18.44) | |||
| Unknown | 2.06 (0.68 to 6.18) | 0.94 (0.12 to 6.95) | |||
| Smoker: | |||||
| No | 1 | 0.35 | 1 | 0.43 | |
| Past | 1.31 (0.72 to 2.39) | 0.52 (0.17 to 1.58) | |||
| Current | 1.78 (0.92 to 3.44) | 0.69 (0.20 to 2.34) | |||
| Unknown | 1.33 (0.75 to 2.35) | 1.28 (0.53 to 3.10) | |||