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Histogram of (C/Dpo)/(C/Div) of tacrolimus (a) and of (C/Dpo)/(C/Div) of tacrolimus according to CYP3A5 genotype (b). The C/D ratio of tacrolimus from just before the change from continuous intravenous infusion (C/Div) was compared with that from 4–7 days after the change to oral administration (C/Dpo). The bars show the median values. *** p < 0.001.
