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. 2019 Apr 26;11(5):948. doi: 10.3390/nu11050948

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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High fat post-weaning diet decreases mice performances in a general anosmia test. The hidden-cookie test measured the effect of maternal and post-weaning diet on general olfactory acuity at 2 months, after 4–5 weeks of post-weaning diet. The test was performed for 3 days (two averaged trials per day) in a fed state and on the 4th day after 8-h fasting. Latencies to find the buried cheese on the first day (a), their evolution between day 1 and 3 (b) and between day 3 (fed) and 4 (fasted) (c) are presented as scatterplots or mean ± SD for female (left; CTRL-CD n = 19, CTRL-HFD n = 20, OB-CD n = 9, OB-HFD n = 10, WL-CD n = 18, WL-HFD n = 16) and male (right; CTRL-CD n = 15, CTRL-HFD n = 16, OB-CD n = 10, OB HFD n = 9, WL-CD n = 16, WL-HFD n = 20) mice.