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. 2019 Apr 26;11(5):948. doi: 10.3390/nu11050948

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Olfactory discrimination is influenced by maternal and post-weaning diets. The habituation/discrimination test measured the ability to discriminate between a sequentially presented set of odours (four successive presentations of pentanol (P1–P4), followed by decanal (D)) at 5.5 months, after 18 weeks of CD or HFD diet. The exploration time for mice in response to the odorant presentation is given as mean ± SD (a) for female (left; CTRL-CD n = 17, CTRL-HFD n = 18, OB-CD n = 7, OB-HFD n = 9, WL-CD n = 15, WL-HFD n = 15) and male (right; CTRL-CD n = 11, CTRL-HFD n = 12, OB-CD n = 7, OB-HFD n = 7, WL-CD n = 12, WL-HFD n = 17). Regression curves for CD-fed and HFD-fed mice during habituation (P1–P4; (b)) for females (left) and male (right).